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SRX17065178: GSM6456099: Subj_6 ULLS [S17]; Homo sapiens; RNA-Seq
1 ILLUMINA (Illumina NovaSeq 6000) run: 149.6M spots, 45.2G bases, 14.1Gb downloads

External Id: GSM6456099_r1
Submitted by: Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health
Study: Ten-day human unilateral lower limb suspension and active recovery in young healthy men
show Abstracthide Abstract
Human skeletal muscle disuse-atrophy is one of the main problems associated with spaceflight, bed rest, lower limb unloading, or immobilization. This study investigates the effects of 10-day unilateral lower limb suspension (ULLS) followed by 21 days of active recovery (AR) in young healthy men. Overall design: 9 subjects with 3 time points each (baseline, 10-day ULLS, 21-day AR), 2 subjects with 2 time points each (baseline, 10-day ULLS), sequenced with RNA-Seq. This submission consists of 31 paired-end RNA-Seq samples.
Sample: Subj_6 ULLS [S17]
SAMN30311118 • SRS14648544 • All experiments • All runs
Organism: Homo sapiens
Library:
Name: GSM6456099
Instrument: Illumina NovaSeq 6000
Strategy: RNA-Seq
Source: TRANSCRIPTOMIC
Selection: cDNA
Layout: PAIRED
Construction protocol: In each participant, a vastus lateralis muscle biopsy (∼150 mg) was collected using a Weil–Blakesley conchotome at ∼2 cm from the motor point. Two ml of lidocaine (2%) were injected in the area of the sampling and a small incision of muscle and fascia was performed. Muscle samples were frozen in liquid nitrogen and stored at −80°C. RNA was extracted from the muscle tissues by REPROCELL (USA) using a Norgen Animal Tissue RNA Purification Kit #257 (Norgen Biotek Corp, Ontario, CA). RNA-Seq was performed at the Frederick National Laboratory for Cancer Research Sequencing Facility, NIH. The libraries were made using the TruSeq Stranded Total RNA Library Prep protocol from Illumina.
Runs: 1 run, 149.6M spots, 45.2G bases, 14.1Gb
Run# of Spots# of BasesSizePublished
SRR21049817149,648,73845.2G14.1Gb2022-09-27

ID:
23857411

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